The Ring Study IPM 027

    The Ring Study (IPM 027) was a Phase III, multi-centre, randomized, double-blind, placebo-controlled safety and efficacy trial of a dapivirine vaginal matrix ring in healthy HIV-negative women. The study was initiated in March 2012, HIV-1 seronegative women between 18-45 years of age were recruited at 7 research centres in South Africa and Uganda. 

    This was the first trial that proved Microbicides to have a significant effect on reduction of HIV transmission. Results were published at the CROI conference, Boston, USA 2017

    Started 2013
    Status completion in 2015 with 138 Participants

    The DREAM study IPM 032

    This study was a follow up, open label study of the Ring study. The study provided additional data to demonstrate the efficacy of the Dapivirine Ring in an open label study.

    • Are people interested in house testing as an early detection method?
    • Are people who test HIV positive looking for care & treatment at an early stage

    Started 2016
    Status completion in 2018 with 89 Participants

    The Autism Study

    The Autism study was a Phase 2B, Multi-Center, Four-Arm, Prospective, Randomized, Double Blind, Placebo-Controlled Trial Evaluating the Efficacy and Safety of 2 Doses of Suramin vs. Placebo in Children with Autism Spectrum Disorder (ASD). The study was activated in October 2019 and closed in May 2021.

    • Are people interested in house testing as an early detection method?
    • Are people who test HIV positive looking for care & treatment at an early stage

    Started 2019
    Status completion in 2021